Former Nickelodeon star Wolff steps into the big time

“The Fault in Our Stars” fans can be a bit like the Mafia.

“Somebody came up to me in the airport like, ‘Nat Wolff? You’re playing Isaac in “The Fault in Our Stars,” right? Don’t f–k it up,’ ” the 19-year-old actor tells The Post. “I was like, ‘Whoa.’ ”

He also couldn’t escape the backlash over his physical differences from the literary character.

“I got a lot of ‘Why aren’t you blond!?!’ tweets,” he says, laughing.

Nat stars as Isaac, a fan favorite. Stricken with eye cancer, Isaac has both of his eyes removed, leaving him blind, which causes his girlfriend to dump him.

Born in LA, Nat is the son of Michael Wolff, the band leader on Arsenio Hall’s 1990s show, and Polly Draper, one of the stars of “thirtysomething.” The teen came to fame alongside his younger brother Alex on the late 2000s Nickelodeon sitcom “The Naked Brothers Band.”

Lately he’s become Hollywood’s new It boy, with buzzy roles in “Admission,” “Palo Alto” and “TFIOS,” as well as director Josh Boone’s “Stuck in Love.” (It was Nat who first showed Boone the script.) He’s already set to star in another John Green adaptation, “Paper Towns.”

Morbid as it may seem, Nat’s

cancer-survivor role provides much of the film’s comic relief. He struggled with that at first, but embraced it after meeting a guy who had gone blind at 19 and was dumped by his girlfriend, just like Isaac.

“He was pissed about it,” says Nat. “I got a lot from him technically — watching him move and deal with his computer [for the visually impaired] — but mostly what I got from him was that edge.”

To prep, Nat spent two days with his eyes shut.

“I ended up putting Tiger Balm on my toothbrush accidentally,” he says. “I almost killed myself.”

Now he’s crossing his fingers that all the work he put in pays off.

“I hope it does justice to blind people and people with cancer, and I hope people who read the book love the movie,” he says. “And, hopefully, they like my brown hair.”