Oprah Winfrey and Michael Jordan attend Surprise Oprah! A Farewell Spectacular at the United Center in Chicago, Illinois.
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Tom Hanks and Oprah Winfrey attend Surprise Oprah! A Farewell Spectacular at the United Center in Chicago, Illinois.
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Will Smith and Oprah Winfrey attend Surprise Oprah! A Farewell Spectacular at the United Center in Chicago, Illinois.
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Jamie Foxx and Oprah Winfrey attend Surprise Oprah! A Farewell Spectacular at the United Center in Chicago, Illinois.
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Usher sings to Oprah Winfrey during the taping of “Oprah’s Surprise Spectacular” in Chicago.
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Oprah Winfrey and Maria Shriver smile during the taping of “Oprah’s Surprise Spectacular” in Chicago.
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President Barack Obama and first lady Michelle Obama are pictured with Oprah Winfrey during a taping of The Oprah Winfrey Show at Harpo Studios in Chicago.
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Oprah Winfrey is shown with “Elvis the Koala” during the taping of her show in Australia.
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Oprah Winfrey talks with Dr. Maya Angelou on the episode of “The Oprah Winfrey Show” that originally aired on April 4, 2002.
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Oprah Winfrey is shown with former President Bill Clinton from the episode of “The Oprah Winfrey Show” that originally aired on June 22, 2004.
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Oprah Winfrey is shown with singer Diana Ross from the episode of “The Oprah Winfrey Show” that originally aired on April 5, 2000.
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Oprah Winfrey is shown with singer Tina Turner from the episode of “The Oprah Winfrey Show” that originally aired on February 17, 1997.
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Oprah Winfrey is shown with guests (L-R) Stevie Wonder, John Travolta, Gayle King and Tina Turner from the Oprah’s 50th Birthday Party episode of “The Oprah Winfrey Show” that originally aired on January 29, 2004.
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Oprah Winfreey gets a kiss from former President George W. Bush during the taping of her show on September 19, 2000.
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Oprah Winfrey is pictured with Mattie Stepanek duirng the taping of her show on October 19, 2001.
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Oprah Winfrey, chairman of OWN: The Oprah Winfrey Network, is joined by singer Will.i.am as she announces the new original programming for the channel’s 2011 launch.
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Oprah Winfrey promotes her upcoming cable channel OWN at the Discovery Communications New York Upfronts in Manhattan.
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Oprah Winfrey introduces the award for Best Actress at the 82nd Academy Awards at the Kodak Theater in Hollywood.
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Oprah Winfrey at the Park Hyatt in Toronto, Canada.
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Oprah Winfrey, Mariah Carey and Mary J. Blige attend the Toronto International Film Festival press conference for “Precious” in Toronto, Canada.
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Oprah Winfrey and best friend Gayle King enjoy a laugh after lunch at Phillipe Chow on Manhattan’s Upper East Side.
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Oprah Winfrey and First Lady Michelle Obama attend Time’s 100 Most Influential People gala in New York City.
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Oprah Winfrey poses with Whitney Houston after the legendary singer’s comeback “Oprah” interview.
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Oprah Winfrey and Whitney Houston hold hands during a live “Oprah” interview at the Town Hall in New York.
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Oprah Winfrey tapes a live show on a three-block stretch of Chicago’s Michigan Avenue near the Chicago River.
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Oprah Winfrey tapes her live show at Central Park in New York City.
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Oprah Winfrey comes to New York City to tape the first two episodes of “The Oprah Winfrey Show.”
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Oprah Winfrey speaks with students at the Oprah Winfrey Leadership Academy for Girls.
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Oprah Winfrey and actresses Thandie Newton and Elizabeth Berkley pose with students at the Oprah Winfrey Leadership Academy for Girls in Henley on Klip, South Africa.
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Jennifer Aniston poses with Oprah Winfrey during a taping of “The Oprah Winfrey Show” in Chicago.
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Oprah Winfrey plays herself on an episode of “30 Rock” with Tina Fey..
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Oprah Winfrey attends the Alvin Ailey American Dance Theater 50th Anniversary Opening Night Gala.
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Oprah Winfrey speaks onstage during the 60th annual Emmy Awards in Los Angeles.
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Oprah receives an honorary degree from Stanford University in Palo Alto, Calif.
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Then-Vice President-elect Joe Biden and wife Jill visit “The Oprah Winfrey Show” at the Kennedy Center Opera House set in Washington, D.C.
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Oprah Winfrey poses with then-Senator Barack Obama and wife Michelle at an Obama ’08 fundraiser hosted by Winfrey at her home in Montecito, Calif.
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Oprah Winfrey joins then-presidential candidate Barack Obama and wife Michelle onstage during a December 2007 rally in Manchester, NH.
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Oprah Winfrey joins Larry King for his 50th Anniversary in Broadcasting celebration at CNN headquarters in LA.
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In summer of 2007, Oprah, pictured here with Tyler Perry, vacations to the Italian Riviera.
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Oprah Winfrey dons sandals after an appearance on “The View” in Manhattan’s Midtown.
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Oprah cries as she receives an honorary degree from Howard University.
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Oprah Winfrey attends the opening night of Broadway show “Three Days of Rain” in Manhattan.
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Oprah Winfrey attends the screening of “Oprah Winfrey’s Legends Ball” in New York City.
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The media mogul during her trip to South Africa in 2007 for the opening of her school for girls.
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Oprah Winfrey opens a self-funded multi-million dollar school for poor South African girls in January 2007 in Johannesburg. Winfrey’s school was the culmination of a pledge she made to Nelson Mandela six years ago, prompting him to heap tributes on her at the glitzy, celebrity-driven opening.
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Oprah Winfrey celebrating after the Oscars.
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Oprah Winfrey laughs it up with Mary J. Blige at the Vanity Fair after party.
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Nicole Kidman, Meryl Streep, Mary J. Blige and Oprah poses for photos during the Vanity Fair Oscar Party.
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Oprah attends the Vanity Fair Oscar Party hosted by Graydon Carter in Hollywood after the 2007 awards show
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Oprah attends the 60th annual Tony Awards at Radio City Music Hall in New York City.
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Oprah Winfrey visits her birthplace, Kosciusko, Mississippi, in 2006 for The Oprah Winfrey Boys & Girls Club, which she helped sponsor.
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In 2006, Oprah attends the opening of the Hearst Tower in NYC.
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Oprah Winfrey arrives to the 17th Annual Women In Entertainment Power 100 Breakfast at the Beverly Hills Hotel in LA.
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Oprah Winfrey is inducted into the NAACP Hall of Fame at the 36th Annual NAACP Image Awards March 2005.
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Oprah Winfrey and Hillary Clinton attend the 2005 International Academy of Televisions Arts & Sciences gala at the Hilton Hotel.
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After visiting Letterman, Oprah Winfrey attended the Broadway opening of “The Color Purple” at the Broadway Theatre.
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Oprah Winfrey returns to chat with David Letterman 16 years after her previous visit to “The Late Show with David Letterman” Dec. 1, 2005.
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Oprah Winfrey poses with Elmo and Archbishop Desmond Tutu during the 2nd annual Sesame Network benefit in New York.
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Oprah Winfrey waves as she arrives for jury duty at the Cook County Criminal Court Building in Chicago.
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Oprah Winfrey leaving the Four Seasons Hotel in New York City.
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Oprah Winfrey shops at Valentino on Manhattan’s Madison Ave.
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Oprah Winfrey squeezes Julia Roberts, who came onto the show for her first interview since announcing that she was pregnant with twins, in 2004.
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Oprah Winfrey and Gayle King attend “Moving Image Salutes John Travolta” at the Waldorf Astoria Hotel in New York City.
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Oprah Winfrey at the 2004 Oscars. .
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Oprah Winfrey walks the red carpet with Halle Berry during the 77th Academy Awards in LA.
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A casual Oprah at the 2004 Nobel Peace Prize awards.
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Oprah returns to the red carpet for the 2004 Academy Awards.
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Oprah Winfrey arrives for the 76th annual Academy Awards in Los Angeles.
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Oprah speaks to a Philly crowd at the Convention Center in 2003.
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Oprah Winfrey plants a big, red one on the cheek of legendary rock star Bono during his appearance on “The Oprah Winfrey Show” in 2002.
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Oprah Winfrey attending the 2002 Vanity Fair after Oscars Party at Morton’s Restaurant in Beverley Hills.
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Oprah Winfrey and Stedman Graham pose together at the ET/GLAMOUR Emmy Party.
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An animated Oprah backstage at the 2002 Emmys.
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Oprah Winfrey and longtime partner Stedman Graham arrive at the 54th annual Emmy Awards in LA.
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A 2002 Oprah walks a red carpet in New York City.
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Venturing into new media, Oprah rolls out O magazine.
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Hillary Clinton and Oprah Winfrey attend the 2000 Essence Awards at Radio City Music Hall New York City.
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Oprah Winfrey jokes with a photographer after leaving Barneys on Madison Ave.
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Stedman Graham, Oprah Winfrey and Gayle King at the Waldorf Astoria Hotel in New York City.
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Stedman Graham and Oprah Winfrey walk the red carpet at the New York premiere of “Beloved” at Manhattan’s Ziegfeld Theatre.
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The talk show host celebrates winning a lawsuit — accusing the media queen of maligning the beef industry — in 1998.
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Oprah Winfrey gleefully displays her People’s Choice Awards trophy for Favorite Female Television Performer.
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Oprah speaks to the audience at the ’96 Emmys.
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Oprah during a 1996 episode.
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Oprah arrives at the 1995 Essence Awards with her longtime partner, Stedman Graham.
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Oprah’s weight has continued to fluctuate ever since – the quickly rising star is pictured here after winning an Emmy for outstanding talk show host in 1994.
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In 1988 – decades before the infamous Tom-Cruise-couch-jumping fiasco – Oprah jumps up and down while showing off her new figure after losing 67 pounds on a liquid diet.Oprah later referred to this show as her “biggest, fattest” mistake. “I had literally starved myself for four months – not a morsel of food – to get into that pair of size 10 Calvin Klein jeans,” said Oprah, who regained 17 of the 67 by 1989.