The experts make their picks:
| THE LINE | GREG GALLO | STEVE SERBY | MARK CANNIZZARO | PAUL SCHWARTZ | TIM BONTEMPS | RICO |
| Colts 3 (43) JAGUARS (Colts 35-31) | Jaguars (L) | Jaguars (L) | ★ Colts (W) | Colts (W) | ★ Colts (W) | Colts (W) |
| SAINTS 7½ (53½) Cowboys (Tomorrow, 8:20, NFLN) | Saints | Cowboys | Saints | Cowboys | Cowboys | Cowboys |
| JETS 6 (40) Falcons (1:00, FOX) | Falcons | Jets | Jets | Jets | Jets | Jets |
| TITANS 3 (41) Dolphins (1:00) | Titans | Dolphins | Dolphins | Dolphins | Titans | Dolphins |
| Patriots 7 (40½) BILLS (1:00) | ★ Patriots | ★ Patriots | ★ Patriots | ★ Patriots | Patriots | Bills |
| Cardinals 12 (47) LIONS (1:00) | ★ Cardinals | Cardinals | Cardinals | ★ Cardinals | Cardinals | ★ Cardinals |
| EAGLES 8½ (42½) 49ers (1:00) | ★ 49ers | ★ 49ers | 49ers | 49ers | Eagles | 49ers |
| RAVENS 11 (40½) Bears (1:00) | Bears | Ravens | Ravens | Ravens | Ravens | Ravens |
| CHIEFS 2 (37) Browns (1:00) | Chiefs | Browns | Browns | Chiefs | Browns | ★ Browns |
| Texans 11 (43) RAMS (1:00) | Texans | ★ Texans | Texans | Rams | Texans | Texans |
| STEELERS 2 (40½) Packers (4:00, FOX) | Packers | Packers | Steelers | Steelers | ★ Packers | Packers |
| CHARGERS 6½ (43½) Bengals (4:00, CBS) | Chargers | Bengals | Chargers | Chargers | Chargers | Bengals |
| BRONCOS 14 (37) Raiders (4:00) | Raiders | Raiders | Raiders | Broncos | Broncos | Raiders |
| SEAHAWKS 6½ (39) Buccaneers (4:00) | Seahawks | Seahawks | Seahawks | ★ Seahawks | ★ Seahawks | ★ Seahawks |
| Vikings 9 (42½) PANTHERS (8:20, NBC) | Panthers | Panthers | ★ Vikings | Panthers | Vikings | Panthers |
| Giants 3 (43½) REDSKINS (Monday, 8:30, ESPN, Ch. 9) | Giants | Giants | Giants | Giants | Redskins | Giants |
Home team in CAPS * Best Bet